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Biology of Aging Books

Clearly, prospective students who wish to work on the biology of aging should start by reading senescence.info's biology of aging section. Still, my own essays may not be adequate for everyone. They may be too complicated for some or not detailed enough for others. Therefore, below are a few book recommendations for students to learn more about gerontology in a variety of ways and at a variety of paces. Have in mind that these are books about the biology of aging, not geriatrics.

Key words: biogerontology, education, graduate, life span, students, undergraduate


Beginner Books

The first book I read about aging was Leonard Hayflick's "How and Why We Age," and I still think it offers a good introduction to the biology of aging. Although Hayflick emphasizes his own field of cellular senescence, he covers different areas and theories. If you have a background in biology, then this is an excellent introductionary book to the biology of aging.

A book in the same line is Robert Arking's "Biology of Aging: Observations & Principles." Arking's book is similar to Hayflick's and it's difficult to choose between the two. Since I read Hayflick's book first, I prefer it, but that may be only my bias. Arking's book also provides a good introduction to the biology of aging and has the advantage of being more recent.

A third book for beginners is Steven Austad's "Why We Age: What Science Is Discovering about the Body's Journey Through Life." Austad uses a more novel-like style, which will appeal to many readers. He also views aging from a different perspective than Hayflick and Arking, so his book may complement the others. On hand I appreciate Austad's overall approach in terms of comparative biology, yet on the other hand I feel his book offers a slightly more limited view regarding theories and mechanisms of aging. Nonetheless, it's a good introductionary book and choosing between these three books is more a matter of personal taste and background than anything else.

Popular Science Books

If you lack the background to read scientific books, works like James Halperin's "The First Immortal" or Damien Broderick's "The Last Mortal Generation: How Science Will Alter Our Lives in the 21st Century" may be more adequate. It's true they don't just talk about aging--Damien Broderick even weaves cosmology and quantum physics into his book--but they remain enjoyable reading experiences that will teach you something about aging along the way.

I tried not to feature edited books--i.e., books in which each chapter is written by a different author--in this essay, but I will open one exception. The Immortality Institute's "The Scientific Conquest of Death: Essays on Infinite Lifespans." The book is divided into two parts: one more scientific, the other more philosophical dealing with the sociological implications of life-extension and research on aging. Both are intriguing and, while not entirely pop science, could serve as a gentle introduction to research on aging. They also provide a different view of aging in that most contributors are not thinking about understanding aging but rather how to cure it. I contributed a chapter to it.

Books for Experts

The best book on aging is Caleb Finch's "Senescence, Longevity, and the Genome." It offers the most complete information on the aging process for a number of species--similar in approach to what Steven Austad does in his book, but much more detailed. It's the sort of book that takes some time to read, not only due to its size but because you want the information to slowly migrate into your brain. But believe me it's worth the time as it will take your knowledge regarding aging to a new level. Being a 1990 book, it's starting to show some signs of aging but that should not serve as an excuse for any gerontologist not to read it. A classic.

One book I very much enjoyed was Kanungo's "Genes and Aging." It present a coherent model of the genetics of aging, linking aging and development but with many other ideas, that I found quite well-thought and reasonable. Definitly not a beginner's book, but very intriguing and full of good ideas.

Bernard Strehler's "Time, Cells, and Aging" offers an interesting and different view on aging. It follows a similar structure to other books featuring demographic models, organ and tissue-level changes, etc., but Strehler's original views on many subjects give it a unique touch. The book loses in its lack of modernity--the 1999 edition has very few changes when compared to earlier versions. Nonetheless, I'd recommend reading it if you wish to deepen your knowledge and learn about many of the older experiments and hypotheses in the science of aging.

There are many books on aging that cover specific topics. One example is Michael Fossel's "Reversing Human Aging." It offers a rather optimistic perspective that the telomeres and telomerase will cure aging. Though a bit outdated now, it's enjoyable to read for those interested in cellular aging. I wouldn't recommend it for beginners though.

Roger Gosden's "Cheating Time" is a book written from the perspective of an endocrinologist. It offers a different view of aging, including some original thoughts on the endocrine system, though I would not recommend it for beginners.

If you are searching information on caloric restriction, then search no further than Richard Weindruch's and Roy Walford's "The Retardation of Aging and Disease by Dietary Restriction." It's still the most complete book on the topic.

Michael Rose's "Evolutionary Biology of Aging," as the name implies, deals with the evolution of aging. It's definitely the best book on the evolution of aging, though the prose is sometimes hard to follow.

Classics

As for old classics, Alex Comfort's book "Ageing, the Biology of Senescence" is still a landmark in the field. It offers a wealth of information, even though somewhat outdated now. For those serious about gerontology, Comfort's book is a good addition to the bookshelf.

August Weismann's 19th century "Essays Upon Heredity and Kindred Biological Problems" is another classic, which includes a few excellent essays on aging: "The Duration of Life" and "Life and Death" are good examples, both in volume one. Certainly it is outdated, but his insights, observations, and hypotheses make this book a good read that I recommend for those serious about the biology of aging.

Peter Medawar's "An Unsolved Problem of Biology," though mostly famous for its discussion of the evolution of aging, is actually a surprising gem with several wonderful, even if often outdated, suggestions.

Conclusion

In conclusion, I recommend you start by reading Hayflick's book, end by reading a book on your specific aging field, and don't forget to read Finch's book somewhere along the way. And please don't forget to check out my own essays on the subject.


The Full List of Mentioned Books

Notice: publisher and publication year refer to the book edition I have read but others may exist.


Arking, Robert; "Biology of Aging: Observations and Principles" (1991). Prentice Hall, Englewood Cliffs, NJ.

Austad, Steven N.; "Why We Age: What Science Is Discovering About the Body's Journey Through Life" (1997). John Wiley & Sons, Inc., NY.

Broderick, Damien; "The Last Mortal Generation: How Science Will Alter Our Lives in the 21st Century" (1999). New Holland, Sydney, Australia.

Comfort, Alex; "Ageing: The Biology of Senescence" (1964). Routledge & Kegan Paul, London.

Finch, Caleb E.; "Senescence, Longevity, and the Genome" (1990). The University of Chicago Press, Chicago and London.

Fossel, Michael; "Reversing Human Aging" (1996). William Morrow and Company, New York.

Gosden, Roger; "Cheating Time" (1996). W. H. Freeman & Company, New York.

Halperin, James L; "The First Immortal" (1998). Del Rey, Random House, NY.

Hayflick, Leonard; "How and Why We Age" (1994). Ballantine Books, NY.

Kanungo, Madhu Sudan; "Genes and Aging" (1994). Cambridge University Press, Cambridge.

Immortality Institute (ed.); "The Scientific Conquest of Death: Essays on Infinite Lifespans" (2004). Libros En Red, Buenos Aires.

Medawar, Peter; "An Unsolved Problem of Biology" (1952). H. K. Lewis, London

Rose, Michael; "Evolutionary Biology of Aging" (1991). Oxford University Press, New York.

Strehler, Bernard; "Time, Cells, and Aging" (1999). Demetriades Brothers, Larnaca.

Weindruch, Richard, and Walford, Roy. "The Retardation of Aging and Disease by Dietary Restriction" (1988). Charles C. Thomas, Springfield, IL.

Weismann, August; "Essays Upon Heredity and Kindred Biological Problems". Volumes 1 & 2 (1891 & 1892). Claredon Press, Oxford.


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